这是一项经美国国家癌症研究所批准的临床三期随机对照试验,目的是研究合并化疗的放射治疗与单纯放射治疗相比,对接受过手术的I-IIA期宫颈癌患者方面的效果如何。放射疗法使用高能X射线杀死肿瘤细胞。用于化疗的药物,如顺铂,以不同的方式阻止肿瘤细胞的生长,或者杀死肿瘤细胞,阻止肿瘤细胞分裂,或者阻止肿瘤细胞扩散。目前尚不清楚放射治疗合并化疗是否比单纯放射治疗更有效地治疗宫颈癌患者。
该临床试验在全美378家医院进行开展。
This randomized phase III trial studies radiation therapy with chemotherapy to see how well they work compared to radiation therapy alone in treating patients with stage I-IIA cervical cancer who previously underwent surgery. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving radiation therapy together with chemotherapy is more effective than radiation therapy alone in treating patients with cervical cancer.